abstract：BACKGROUND:Klebsiella pneumoniae can be found in environmental habitats as well as in hospital settings where it is commonly associated with nosocomial infections. One of the factors that contribute to virulence is its capacity to form biofilms on diverse biotic and abiotic surfaces. The second messenger Bis-(3'-5')-cy...

journal_title：BMC microbiology

authors： Cruz DP,Huertas MG,Lozano M,Zárate L,Zambrano MM

更新日期：2012-07-09 00:00:00

abstract：BACKGROUND:Streptococcus pseudopneumoniae, is a novel member of the genus Streptococcus, falling close to related members like S. pneumoniae, S. mitis, and S. oralis. Its recent appearance has shed light on streptococcal infections, which has been unclear till recently. In this study, the transcriptome of S. pseudopneu...

journal_title：BMC microbiology

authors： Park HK,Myung SC,Kim W

更新日期：2012-07-06 00:00:00

abstract：BACKGROUND:Glycopeptidolipids (GPLs) are among the major free glycolipid components of the outer membrane of several saprophytic and clinically-relevant Mycobacterium species. The architecture of GPLs is based on a constant tripeptide-amino alcohol core of nonribosomal peptide synthetase origin that is N-acylated with ...

journal_title：BMC microbiology

authors： Tatham E,Sundaram Chavadi S,Mohandas P,Edupuganti UR,Angala SK,Chatterjee D,Quadri LE

更新日期：2012-06-22 00:00:00

abstract：BACKGROUND:The sequenced O45:K1:H7 Escherichia coli meningitis strain S88 harbors a large virulence plasmid. To identify possible genetic determinants of pS88 virulence, we examined the transcriptomes of 88 plasmidic ORFs corresponding to known and putative virulence genes, and 35 ORFs of unknown function. RESULTS:Qua...

journal_title：BMC microbiology

authors： Lemaître C,Bidet P,Bingen E,Bonacorsi S

更新日期：2012-06-21 00:00:00

abstract：BACKGROUND:Recent studies have identified in Mycobacterium avium subsp. paratuberculosis (MAP), already known as a pathogen in ruminants, a potential zoonotic agent of some autoimmune diseases in humans. Therefore, considering the possible risk for public health, it is necessary a thorough understanding of MAP's gene e...

journal_title：BMC microbiology

authors： Cossu A,Sechi LA,Zanetti S,Rosu V

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Rhizobium tropici strain PRF 81 (= SEMIA 4080) has been used in commercial inoculants for application to common-bean crops in Brazil since 1998, due to its high efficiency in fixing nitrogen, competitiveness against indigenous rhizobial populations and capacity to adapt to stressful tropical conditions, repr...

journal_title：BMC microbiology

authors： Gomes DF,Batista JS,Schiavon AL,Andrade DS,Hungria M

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Recent studies suggest that the reported protective effects of statins (HMG-CoA reductase inhibitors) against community-acquired pneumonia (CAP) and sepsis in humans may be due to confounders and a healthy user-effect. To directly test whether statins are protective against Streptococcus pneumoniae, the lead...

journal_title：BMC microbiology

authors： Boyd AR,Hinojosa CA,Rodriguez PJ,Orihuela CJ

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:Bacteria release a wide variety of small molecules including cell-to-cell signaling compounds. Gram-negative bacteria use a variety of self-produced autoinducers such as acylated homoserine lactones (acyl-HSLs) as signal compounds for quorum sensing (QS) within and between bacterial species. QS plays a signi...

journal_title：BMC microbiology

authors： Minagawa S,Inami H,Kato T,Sawada S,Yasuki T,Miyairi S,Horikawa M,Okuda J,Gotoh N

更新日期：2012-05-10 00:00:00

abstract：BACKGROUND:Similar to Gram-negative bacteria, the outer membrane (OM) of the pathogenic spirochete, Borrelia burgdorferi, contains integral OM-spanning proteins (OMPs), as well as membrane-anchored lipoproteins. Although the mechanism of OMP biogenesis is still not well-understood, recent studies have indicated that a ...

journal_title：BMC microbiology

authors： Lenhart TR,Kenedy MR,Yang X,Pal U,Akins DR

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:The genus Xanthomonas comprises several plant pathogenic bacteria affecting a wide range of hosts. Despite the economic, industrial and biological importance of Xanthomonas, the classification and phylogenetic relationships within the genus are still under active debate. Some of the relationships between pat...

journal_title：BMC microbiology

authors： Rodriguez-R LM,Grajales A,Arrieta-Ortiz ML,Salazar C,Restrepo S,Bernal A

更新日期：2012-03-23 00:00:00

abstract：BACKGROUND:Bacteria excrete costly toxins to defend their ecological niche. The evolution of such antagonistic interactions between individuals is expected to depend on both the social environment and the strength of resource competition. Antagonism is expected to be weak among highly similar genotypes because most ind...

journal_title：BMC microbiology

authors： Schoustra SE,Dench J,Dali R,Aaron SD,Kassen R

更新日期：2012-03-22 00:00:00

abstract：BACKGROUND:The high demand for ethanol in the U.S. has generated large stocks of wet distillers grains (DG), a byproduct from the manufacture of ethanol from corn and sorghum grains. Little is known, however, about the potential influence of dietary DG on fecal microbial community structure. A better understanding of t...

journal_title：BMC microbiology

authors： Rice WC,Galyean ML,Cox SB,Dowd SE,Cole NA

更新日期：2012-02-24 00:00:00

abstract：BACKGROUND:Central nervous system disease is the most serious form of tuberculosis, and is associated with high mortality and severe neurological sequelae. Though recent clinical reports suggest an association of distinct Mycobacterium tuberculosis strains with central nervous system disease, the microbial virulence fa...

journal_title：BMC microbiology

authors： Be NA,Bishai WR,Jain SK

更新日期：2012-01-13 00:00:00

abstract：BACKGROUND:The genus Brucella contains highly infectious species that are classified as biological threat agents. The timely detection and identification of the microorganism involved is essential for an effective response not only to biological warfare attacks but also to natural outbreaks. Matrix-assisted laser desor...

journal_title：BMC microbiology

authors： Lista F,Reubsaet FA,De Santis R,Parchen RR,de Jong AL,Kieboom J,van der Laaken AL,Voskamp-Visser IA,Fillo S,Jansen HJ,Van der Plas J,Paauw A

更新日期：2011-12-23 00:00:00

abstract：BACKGROUND:Accumulation of gyrase cleavage complex in Escherichia coli from the action of quinolone antibiotics induces an oxidative damage cell death pathway. The oxidative cell death pathway has also been shown to be involved in the lethality following accumulation of cleavage complex formed by bacterial topoisomeras...

journal_title：BMC microbiology

authors： Liu IF,Aedo S,Tse-Dinh YC

更新日期：2011-12-12 00:00:00

abstract：BACKGROUND:Urine within the urinary tract is commonly regarded as "sterile" in cultivation terms. Here, we present a comprehensive in-depth study of bacterial 16S rDNA sequences associated with urine from healthy females by means of culture-independent high-throughput sequencing techniques. RESULTS:Sequencing of the V...

journal_title：BMC microbiology

authors： Siddiqui H,Nederbragt AJ,Lagesen K,Jeansson SL,Jakobsen KS

更新日期：2011-11-02 00:00:00

abstract：BACKGROUND:Indoor microbial contamination due to excess moisture is an important contributor to human illness in both residential and occupational settings. However, the census of microorganisms in the indoor environment is limited by the use of selective, culture-based detection techniques. By using clone library sequ...

journal_title：BMC microbiology

authors： Pitkäranta M,Meklin T,Hyvärinen A,Nevalainen A,Paulin L,Auvinen P,Lignell U,Rintala H

更新日期：2011-10-21 00:00:00

abstract：BACKGROUND:Most living cells uptake phosphate, an indispensable nutrient for growth from their natural environment. In Synechocystis sp. PCC 6803, the cells lack phosphate-inorganic transport (Pit) system but contain two phosphate-specific transport (Pst) systems, Pst1 and Pst2. We investigated the kinetics of Pi uptak...

journal_title：BMC microbiology

authors： Burut-Archanai S,Eaton-Rye JJ,Incharoensakdi A

更新日期：2011-10-11 00:00:00

abstract：BACKGROUND:Epidemiology of celiac disease (CD) is increasing. CD mainly presents in early childhood with small intestinal villous atrophy and signs of malabsorption. Compared to healthy individuals, CD patients seemed to be characterized by higher numbers of Gram-negative bacteria and lower numbers Gram-positive bacter...

journal_title：BMC microbiology

authors： Di Cagno R,De Angelis M,De Pasquale I,Ndagijimana M,Vernocchi P,Ricciuti P,Gagliardi F,Laghi L,Crecchio C,Guerzoni ME,Gobbetti M,Francavilla R

更新日期：2011-10-04 00:00:00

abstract：BACKGROUND:Campylobacter jejuni is a leading foodborne pathogen worldwide. Despite the fastidious nature of C. jejuni growth, increasing numbers of human campylobacteriosis suggest that C. jejuni may possess unique mechanisms to survive under various stress conditions. C. jejuni possesses only three sigma factors (FliA...

journal_title：BMC microbiology

authors： Hwang S,Jeon B,Yun J,Ryu S

更新日期：2011-09-22 00:00:00

abstract：BACKGROUND:Many bacterial extracytoplasmic proteins are stabilized by intramolecular disulfide bridges that are formed post-translationally between their cysteine residues. This protein modification plays an important role in bacterial pathogenesis, and is facilitated by the Dsb (disulfide bond) family of the redox pro...

journal_title：BMC microbiology

authors： Grabowska AD,Wandel MP,Łasica AM,Nesteruk M,Roszczenko P,Wyszyńska A,Godlewska R,Jagusztyn-Krynicka EK

更新日期：2011-07-25 00:00:00

abstract：BACKGROUND:Enterococci are increasingly associated with opportunistic infections in Humans but the role of the oral cavity as a reservoir for this species is unclear. This study aimed to explore the carriage rate of Enterococci in the oral cavity of Tunisian children and their antimicrobial susceptibility to a broad ra...

journal_title：BMC microbiology

authors： Kouidhi B,Zmantar T,Mahdouani K,Hentati H,Bakhrouf A

更新日期：2011-06-29 00:00:00

abstract：BACKGROUND:Many chronic diseases, such as non-healing wounds are characterized by prolonged inflammation and respond poorly to conventional treatment. Bacterial biofilms are a major impediment to wound healing. Persistent infection of the skin allows the formation of complex bacterial communities termed biofilm. Bacter...

journal_title：BMC microbiology

authors： Secor PR,James GA,Fleckman P,Olerud JE,McInnerney K,Stewart PS

更新日期：2011-06-21 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is a food-borne pathogen and the most common cause of infections in hospitalized patients. The increase in the resistance of this pathogen to antibacterials has made necessary the development of new anti-staphylococcal agents. In this context, bacteriophage lytic enzymes such as endolys...

journal_title：BMC microbiology

authors： Rodríguez L,Martínez B,Zhou Y,Rodríguez A,Donovan DM,García P

更新日期：2011-06-17 00:00:00

abstract：BACKGROUND:Escherichia coli is a well-studied anaerobic bacteria which is able to regulate metabolic pathways depending on the type of sugar presented in the medium. We have studied the glucose-lactose shift in E. coli at the protein level using a recently developed mass spectrometry platform. METHOD:Cells were grown ...

journal_title：BMC microbiology

authors： Mostovenko E,Deelder AM,Palmblad M

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Candida parapsilosis typically is a commensal of human skin. However, when host immune defense is compromised or the normal microflora balance is disrupted, C. parapsilosis transforms itself into an opportunistic pathogen. Candida-derived lipase has been identified as potential virulence factor. Even though ...

journal_title：BMC microbiology

authors： Nagy I,Filkor K,Németh T,Hamari Z,Vágvölgyi C,Gácser A

更新日期：2011-05-29 00:00:00

abstract：BACKGROUND:Bacterial adhesive proteins, called adhesins, are frequently the decisive factor in initiation of a bacterial infection. Characterization of such molecules is crucial for the understanding of bacterial pathogenesis, design of vaccines and development of antibacterial drugs. Because adhesins are frequently di...

journal_title：BMC microbiology

authors： Kylväjä R,Kankainen M,Holm L,Westerlund-Wikström B

更新日期：2011-05-27 00:00:00

abstract：BACKGROUND:Cystic fibrosis (CF) lung disease has a unique profile of pathogens predominated by Pseudomonas aeruginosa (PsA) and Staphylococcus aureus (SA). These microorganisms must overcome host immune defense to colonize the CF lungs. Polymorphonuclear neutrophils are a major component of the host defense against bac...

journal_title：BMC microbiology

authors： Bonvillain RW,Painter RG,Ledet EM,Wang G

更新日期：2011-05-20 00:00:00

abstract：BACKGROUND:Fluconazole (FLC), a triazole antifungal drug, is widely used for the maintenance therapy of cryptococcal meningoencephalitis, the most common opportunistic infection in AIDS patients. In this study, we examined changes in the gene expression profile of the C. neoformans reference strain H99 (serotype A) fol...

journal_title：BMC microbiology

authors： Florio AR,Ferrari S,De Carolis E,Torelli R,Fadda G,Sanguinetti M,Sanglard D,Posteraro B

更新日期：2011-05-11 00:00:00

abstract：BACKGROUND:Compared with many protists, Giardia lamblia has a simple life cycle alternating between cyst and trophozoite. Most research on the molecular biology of Giardia parasites has focused on trophozoites and the processes of excystation and encystation, whereas cysts have attracted less interest. The striking mor...

journal_title：BMC microbiology

authors： Faghiri Z,Widmer G

更新日期：2011-05-04 00:00:00

abstract：BACKGROUND:Klebsiella pneumoniae displaying the hypermucoviscosity (HV) phenotype are considered more virulent than HV-negative strains. Nevertheless, the emergence of tissue-abscesses-associated HV-negative isolates motivated us to re-evaluate the role of HV-phenotype. RESULTS:Instead of genetically manipulating the ...

journal_title：BMC microbiology

authors： Lin YC,Lu MC,Tang HL,Liu HC,Chen CH,Liu KS,Lin C,Chiou CS,Chiang MK,Chen CM,Lai YC

更新日期：2011-03-08 00:00:00

abstract：BACKGROUND:Streptococcus suis is a major swine pathogen worldwide that causes meningitis, septicemia, arthritis, and endocarditis. Using animal models, a surface-associated subtilisin-like protease (SspA) has recently been shown to be an important virulence factor for S. suis. In this study, we hypothesized that the S....

journal_title：BMC microbiology

authors： Bonifait L,Grenier D

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Zinc is an essential element for all living cells. Recent studies have shown that the ZnuABC zinc uptake system significantly contributes to the ability of several pathogens to multiply in the infected host and cause disease, suggesting that zinc is scarcely available within different tissues of the host. To...

journal_title：BMC microbiology

authors： Gabbianelli R,Scotti R,Ammendola S,Petrarca P,Nicolini L,Battistoni A

更新日期：2011-02-21 00:00:00

abstract：BACKGROUND:Clostridium thermocellum is a Gram-positive thermophilic anaerobic bacterium with the unusual capacity to convert cellulosic biomass into ethanol and hydrogen. Identification and characterization of protein complexes in C. thermocellum are important toward understanding its metabolism and physiology. RESULT...

journal_title：BMC microbiology

authors： Peng Y,Luo Y,Yu T,Xu X,Fan K,Zhao Y,Yang K

更新日期：2011-01-26 00:00:00

abstract：BACKGROUND:The purpose of this study was to design and evaluate fluorescent in situ hybridization (FISH) probes for the single-cell detection and enumeration of lactic acid bacteria, in particular organisms belonging to the major phylogenetic groups and species of oral lactobacilli and to Abiotrophia/Granulicatella. R...

journal_title：BMC microbiology

authors： Quevedo B,Giertsen E,Zijnge V,Lüthi-Schaller H,Guggenheim B,Thurnheer T,Gmür R

更新日期：2011-01-19 00:00:00

abstract：BACKGROUND:"Candidatus Phytoplasma aurantifolia", is the causative agent of witches' broom disease in Mexican lime trees (Citrus aurantifolia L.), and is responsible for major losses of Mexican lime trees in Southern Iran and Oman. The pathogen is strictly biotrophic, and thus is completely dependent on living host cel...

journal_title：BMC microbiology

authors： Zamharir MG,Mardi M,Alavi SM,Hasanzadeh N,Nekouei MK,Zamanizadeh HR,Alizadeh A,Salekdeh GH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Vibrio parahaemolyticus is a food-borne pathogen causing inflammation of the gastrointestinal epithelium. Pathogenic strains of this bacterium possess two Type III Secretion Systems (TTSS) that deliver effector proteins into host cells. In order to better understand human host cell responses to V. parahaemol...

journal_title：BMC microbiology

authors： Matlawska-Wasowska K,Finn R,Mustel A,O'Byrne CP,Baird AW,Coffey ET,Boyd A

更新日期：2010-12-30 00:00:00

abstract：BACKGROUND:Rhodobacter sphaeroides 2.4.1 is a metabolically versatile organism that belongs to α-3 subdivision of Proteobacteria. The present study was to identify the extent, history, and role of gene duplications in R. sphaeroides 2.4.1, an organism that possesses two chromosomes. RESULTS:A protein similarity search...

journal_title：BMC microbiology

authors： Bavishi A,Lin L,Schroeder K,Peters A,Cho H,Choudhary M

更新日期：2010-12-30 00:00:00

abstract：BACKGROUND:Pandemic Vibrio parahaemolyticus has undergone rapid changes in both K- and O-antigens, making detection of outbreaks more difficult. In order to understand these rapid changes, the genetic regions encoding these antigens must be examined. In Vibrio cholerae and Vibrio vulnificus, both O-antigen and capsular...

journal_title：BMC microbiology

authors： Chen Y,Dai J,Morris JG Jr,Johnson JA

更新日期：2010-11-02 00:00:00

abstract：BACKGROUND:Bacteria belonging to Planctomycetes display several unique morphological and genetic features and are found in a wide variety of habitats on earth. Their ecological roles in these habitats are still poorly understood. Planctomycetes have previously been detected throughout the year on surfaces of the kelp L...

journal_title：BMC microbiology

authors： Bengtsson MM,Øvreås L

更新日期：2010-10-15 00:00:00